Effectiveness of atypical antipsychotics on anhedonic features in patients with schizophrenia - PLEASURE

Inclusion Criteria

• Inclusion Criteria:
• - Documented clinical diagnosis of schizophrenia meeting the Diagnostic and Statistical Manual of Mental Disorders,(DSM-IV-TR) criteria
• - Patients who already take one atypical at inclusion it is started at least 1 week and up to 4 weeks before the inclusion
• Exclusion Criteria:
• - Meeting the criteria for any other (than schizophrenia) DSM-IV Axis I
• - Patients with antipsychotic combinations (more than two agents)
• - Patients who are already on any mood stabilizers and antidepressant
• - Known lack of response to clozapine or treatment with clozapine within 4 weeks prior to enrollment
• - Patients who have been treated with antipsychotics in depot formulations for the last two months
• - Previous enrollment or randomisation of treatment in the present NIS
• - Patients who had participated in other clinical trials within 4 weeks prior to enrollment period
• - Pregnant women or women who are breast-feeding