Drug-drug interaction study of Esomeprazole (D961H) capsule and loxoprofen tablet after repeated oral administration in Japanese males

Exclusion Criteria

• - Past or present NSAIDs induced asthma, hepatic dysfunction, peptic ulcer or blood disorders
• - Significant clinical illness from the 2 weeks preceding the pre-entry visit to the randomisation, as judged by the investigator(s) , eg, acute inflammatory disease which requires medical intervention
• - Past or present cardiac, renal, hepatic, neurological or gastrointestinal disease, as judged by the investigator(s), eg, sequelae of myocardial infarction, nephritis, hepatitis and cerebral infarction