A Study to Evaluate Cortisol Reserve in Response to Adrenocorticotropic Hormone (ACTH) Stimulation Test Following Baxdrostat Treatment Compared to Placebo in Participants with Uncontrolled Hypertension

Study identifier:D6970C00011

ClinicalTrials.gov identifier:NCT06336356

EudraCT identifier:N/A

CTIS identifier:N/A

Recruitment Complete

Official Title

A Randomised, Double-blind, Placebo-controlled Study to Evaluate Cortisol Reserve in Response to Adrenocorticotropic Hormone Stimulation Test Following Treatment with Baxdrostat for 8 Weeks in Participants with Uncontrolled Hypertension

Medical condition

Uncontrolled Hypertension

Phase

Phase 2

Healthy volunteers

No

Study drug

Baxdrostat, Placebo

Sex

All

Actual Enrollment

48

Study type

Interventional

Age

18 Years - 130 Years

Date

Study Start Date: 10 Jun 2024
Estimated Primary Completion Date: 15 Nov 2024
Estimated Study Completion Date: 15 Nov 2024

Study design

Allocation: Randomized
Endpoint Classification: -
Intervention Model: Parallel Assignment
Masking: -
Primary Purpose: Treatment

Verification:

Verified 01 Oct 2024 by AstraZeneca

Sponsors

AstraZeneca

Collaborators

-

Inclusion and exclusion criteria