Assessing a Stool Symptom Screener in Patients with Chronic Opioid-Induced Constipation

Inclusion Criteria

• Inclusion Criteria:
• - Receiving a stable maintenance opioid regimen (total daily dose of 30-1000mg of oral morphine, or equianalgesic amounts of 1 or more other opioid therapies) for a minimum of 4 weeks for non-cancer related pain.
• - Development of constipation symptoms since starting opioids.
• - Taken laxatives to help with bowel movements for at least four days over the past 2 weeks.
• Exclusion Criteria:
• - Receiving opioid regimen for treatment of pain related to cancer.
• - Participated in any clinical trial or research study relating to opioid use and/or constipation within the past year.
• - History of cancer within 5 years from the time of screening.
• - Has medical condition(s) and/or treatment(s) associated with diarrhea, intermittent loose stools, or constipation (e.g., fecal incontinence or chronic idiopathic constipation).
• - Has irritable bowel syndrome (IBS) or chronic functional constipation.