Oral AZD8165 after single oral ascending doses in healthy male subjects

Exclusion Criteria

• - History of any clinically significancy disease or disorder which, in the opinion of the Investigator, may either put the volunteer at risk because of participation in the study, or influence the results or the volunteer's ability to participate in the study
• - History or presence of gastrointestinal, hepatic or renal disease or any other condition known to interfere with absorption, distribution, metabolism or excretion of drugs
• - Personal or family history of bleeding disorders, or reasonable suspicion of vascular malformations, including aneurysms.