Seroquel in Bipolar Depression versus Lithium

Inclusion Criteria

• Inclusion Criteria:
• - Patients with a diagnosis of bipolar I disorder or bipolar II disorder, currently depressed, aged 18 to 65 years old and outpatient status at enrolment and randomization.
• Exclusion Criteria:
• - Patients with a current DSM-IV Axis I disorder other than bipolar disorder that is symptomatic or requiring treatment within 6 months of enrolment,
• - History of non-response to an adequate treatment
• - Patients who, in the investigator’s judgment pose a current serious suicidal or homicidal risk
• - Pregnancy or lactation
• - Clinically relevant disease or clinical finding