Non-interventional study of patients with PN NF1 starting selumetinib in Russia

Exclusion Criteria

• - Patients currently participating in an interventional study/clinical trial,
• - Patients are excluded if there is evidence of an optic glioma, malignant glioma, malignant peripheral nerve sheath tumor, or other cancer, requiring treatment with chemotherapy or radiation therapy,
• - Patients who receive other antitumor treatment options on optic nerve glioma, malignant glioma, malignant tumor of the peripheral nerve sheath, or other cancer. If the patient on selumetinib treatment develop optic nerve glioma, malignant glioma, malignant tumor of the peripheral nerve sheath, or other cancer, he can continue selumetinib therapy +\- other treatment options on physician decision,
• - Female patients above 12 age who are pregnant /plan to become pregnant or at breast feeding.