Safety, tolerability & PK of AZD0328 in Caucasian & Japanese

Exclusion Criteria

• - History of clinically significant cardio- or cerebrovascular, pulmonary, renal, hepatic, neurological, mental or gastrointestinal disorder or any other major disorder that may interfere with the study.
• - Participation in another study within 12 weeks before the first administration of the investigational product.
• - Intake of any prescribed medicine or herbal remedies based on St John’s Wort, except for occasional paracetamol and nasal adrenergic anticongestants, within 3 weeks before the first administration of the investigational product.