A study to investigate the effect of rosuvastatin (CRESTOR®) on high density lipoprotein kinetics in patients with the metabolic syndrome

Inclusion Criteria

• - Signed informed consent
• - male aged 30 to 70 years of age
• - LDL-C <6 mmol/L
• - HDL-C ≤1.2 mmol/L
• - at least 2 of the following:
• - insulin resistance (fasting glucose >6 mmol/L or insulin >10 mU/L or HOMA score >2.5)
• - central obesity (waist circumference >=94 cm).
• - plasma triglycerides >=1.7 and <4.5 mmol/L.
• - blood pressure >=130/ >=85 mm Hg or on drug treatment for hypertension